畜牧兽医学报 ›› 2015, Vol. 46 ›› Issue (7): 1077-1083.doi: 10.11843/j.issn.0366-6964.2015.07.001

• 综述 • 上一篇    下一篇

脑-肠轴及其在动物摄食调控中的作用

刘飞飞1,2,秦贵信1,2*,姜海龙1,孙泽威1   

  1. (1.吉林农业大学动物科学技术学院,长春 130118; 2.动物生产与产品质量安全教育部重点实验室,长春 130118)
  • 收稿日期:2014-12-03 出版日期:2015-07-23 发布日期:2015-07-23
  • 通讯作者: 秦贵信,教授,博士生导师,E-mail:qgx@jlau.edu.cn
  • 作者简介:刘飞飞(1985-),女,吉林长春人,博士生,主要从事动物营养学研究,E-mail:feikathy@163.com
  • 基金资助:

    产业技术创新战略联盟项目(20140309013NY);国家科技支撑计划项目(2012BAD39B03)

Advanced of Brain-gut Axis and Its Role in Modulating Food Intake of Animals

LIU Fei-fei1,2,QIN Gui-xin1,2* ,JIANG Hai-long1,SUN Ze-wei1   

  1. (1.College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China;2.Key Laboratory of Animal Production,Product Quality and Security,Ministry of Education,Changchun 130118,China)
  • Received:2014-12-03 Online:2015-07-23 Published:2015-07-23

摘要:

摄食是动物的一种反射性活动,动物摄食行为的调节与脑-肠轴密切相关。动物摄食后,营养物质接触胃肠道从而刺激脑肠肽的释放,通过迷走传入神经元将信号传递给中枢神经系统,神经中枢将信号整合后经传出神经到达效应器官以促进或抑制摄食。脑-肠肽是参与食物摄取的重要的胃肠激素,在脑-肠轴调控摄食行为中起关键的作用,本文就脑-肠轴参与摄食调节作用方面的研究进展作一综述。

Abstract:

 Feeding is a reflective activity in animals,and regulation of feeding behavior is associated with brain-gut axis.After feeding,brain-gut peptides were released from gastrointestinal after receiving signal stimuli of nutrients,vagal afferent neurons received signal of brain-gut peptides and transferred them to central nervous system,which integrated these signals to effector organ and promoted or inhibited feeding.Brain-gut peptides,important gastrointestinal hormones involved in food intake,are playing a critical role in the regulation of feeding behavior of brain-gut axis.The advances on food intake regulation of brain-gut axis are reviewed in this article.

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